By Dr. Rinku Ratti MBBS (distinction) MRCGP (distinction) BSc (Honours) DFFP DRCOG. – Aesthetic and Medical Doctor at The Doctor’s Practice, Birmingham.

New ingredients and treatments emerge constantly, each promising to deliver remarkable results. One such ingredient that has been garnering significant attention lately is polynucleotides. But what exactly are polynucleotides, and why are they so beneficial for your skin? Dr Rinku dives into the science behind this innovative skincare ingredient and explore its myriad benefits.

Polynucleotides are long chains of nucleotides, which are the basic building blocks of DNA and RNA. DNA and RNA are two examples of polynucleotides. The polynucleotides used in cosmetic medicine to remodel the skin are made up of highly purified fragments of DNA extracted from wild salmon or trout sperm. The trout used are the same as used for food. Salmon and trout sperm DNA closely resembles human DNA.

Are they safe to inject?

Dr Rinku explains clarifies that the polynucleotides are highly purified and then sterilised from a licensed source, the production is regulated and the manufacture meets required CE standards of safety. All the protein molecules are removed, so there is no risk of allergy. Dr Rinku says this science is evidenced based and there are multiple published scientific papers demonstrating safety and efficacy in medicine for the treatment of tissue injury and also in aesthetic medicine. There are no known risks associated with the injection of exogenous (Non-self) polynucleotides.

The reason Dr Rinku loves polynucleotides because they can treat such a large variety of skin concerns and conditions and produce long lasting results for:

● Dull skin

● Course skin

● Wrinkles

● Uneven Pigmentation

● Redness

● Dark circles

● Acne scarring

● Stretch marks

● Surgical scarring

● Hair loss

● Intimate ares – dryness, itching, dehydration, loss of volume

● Not just for the face; hands, neck, chest, arms, knees. Any skin, anywhere on the body.

Dr Rinku explains the benefits of Polynucleotides for Your Skin

  1. Enhanced Skin Regeneration: Polynucleotides are renowned for their ability to promote cellular regeneration. When applied to the skin, they stimulate the production of new skin cells and help repair damaged tissues. This regenerative property makes polynucleotides particularly effective in treating scars, wrinkles, and other signs of aging.
  2. Improved Hydration: One of the key functions of polynucleotides is to enhance the skin’s natural ability to retain moisture. By boosting the production of hyaluronic acid and other moisture-binding molecules, polynucleotides help keep the skin hydrated, plump, and youthful-looking.
  3. Anti-Inflammatory Properties: Polynucleotides have been found to possess potent anti-inflammatory properties. This makes them highly effective in soothing irritated skin, reducing redness, and treating conditions such as acne and rosacea. Their ability to calm inflammation also contributes to overall skin health and longevity.
  4. Enhanced Elasticity and Firmness: As we age, our skin’s natural production of collagen and elastin diminishes, leading to sagging and loss of firmness. Polynucleotides stimulate the synthesis of these essential proteins, improving skin elasticity and firmness. This results in a more lifted and toned appearance.
  5. Antioxidant Protection: Polynucleotides are rich in antioxidants, which help protect the skin from free radical damage caused by environmental factors such as UV radiation and pollution. By neutralizing these harmful molecules, polynucleotides prevent premature aging and maintain the skin’s youthful glow.
  6. Enhanced Wound Healing: Due to their regenerative properties, polynucleotides can accelerate the healing process of wounds and other skin injuries. This makes them an excellent ingredient for post-procedural skincare, helping to speed up recovery and minimise downtime.

Polynucleotides stimulate a receptor on cells which positively influences the following

● Cell proliferation and regeneration

● The repair and regenerative actions of fibroblast cells

● The production of collagen and elastin

● The production of hyaluronic acid

● The production of healthy new micro-blood vessels

● The function of melanocytes which produce pigment.

● They reduce inflammation

● Regulate water balance

● Regulate the formation of fat cells

● Regenerate hair follicles

The use of polynucleotides in regenerative medicine is well established in tissue repair, following traumatic injury or surgery.

What does treatment involve?

The polynucleotides are distilled into a range of strengths and suspended in water for injection. They are injected into the superficial layer of the skin. Dr Rinku uses either a fine needle or a cannula to administer multiple micro-doses into the target area. Usually a numbing cream is applied before treatment to make it as comfortable as possible.

A course of three or four treatments 3 weeks apart is recommended to achieve optimum results.

What results can I expect?

The results are not instant but improvement can be noted from about three weeks and continues to improve over a twelve week period. Patients report a general improvement in the skin should feel smoother and better hydrated, the texture can be improved. Fine lines and wrinkles are improved. Scarring can be improved, with less depth, smaller and better colour.

When hair loss is the concern being addressed, new hair growth can be noted and existing hair will be healthier.

When you use the polynucleotides on the intimate areas, you can experience more hydration,less dryness, and a reduction of itchiness.

Results will vary between individuals as the outcome is dependent upon the biological response of the individual and also lifestyle factors.

How long do results last?

Longevity does vary between individuals. Polynucleotides do not arrest the ageing process, therefore a maintenance treatment is recommended every six months. Life-style factors can effect longevity. If you choose not to maintain the results with further treatment, your skin will return to its pre-treatment state over time.

Polynucleotides represent a groundbreaking advancement in skincare, offering a wide range of benefits from enhanced regeneration and hydration to anti-inflammatory and antioxidant protection. By incorporating polynucleotides into your skincare routine, you can achieve healthier, more youthful-looking skin. As with any new skincare ingredient, it’s essential to choose high-quality products and consult with us at The Doctors Practice to plan your individual treatment plan tailored to your skin needs. Embrace the power of polynucleotides and unlock the secret to radiant, rejuvenated skin.

Dr Rinku

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